Immune disease risk variants regulate gene expression dynamics

Description

Dynamic effects of genetic variation on gene expression revealed following hypoxic stress in cardiomyocytes

Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation

A molecular map of T cell activation gives insights into immune disease

Frontiers Polygenic risk associated with Alzheimer's disease and other traits influences genes involved in T cell signaling and activation

The emerging role of epigenetics in human autoimmune disorders, Clinical Epigenetics

Mapping the functional impact of non-coding regulatory elements in primary T cells through single-cell CRISPR screens, Genome Biology

IJMS, Free Full-Text

Exploring the dynamics and influencing factors of CD4 T cell activation using single-cell RNA-seq - ScienceDirect

Genes, Free Full-Text

Study tracking T-cell activation over time boosts search for immune disease treatments - Open Targets

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