Update of Individualized Treatment Strategies for Postural Orthostatic Tachycardia Syndrome in Children

Individualized management strategies based on different subtypes of POTS would largely improve the curative effects of drugs for children with POTS, and further clinical investigation is still required to better understand the pathophysiology and treatment options. Postural orthostatic tachycardia syndrome (POTS) is a heterogeneous disease that predominantly affects children and adolescents. There is a great difference between children and adults in the diagnosis and treatment of POTS patients. POTS in children and adolescents is marked by chronic symptoms of orthostatic intolerance with a heart rate (HR) rise of ≥40 bpm, or heart rate exceeding 130 bpm for 6–12-years-old children and exceeding 125 bpm for those 13–18 years old without orthostatic hypotension, which is different from adult patients. The three major clinical forms of POTS include hypovolemic POTS, neuropathic POTS, and hyperadrenergic POTS; these are distinguished by their major mechanisms. The different subtypes of POTS in children and adolescents each have their own clinical characteristics and biomarkers. Based on these, we propose individualized treatment strategies. Individualized management strategies based on different subtypes of POTS would largely improve the curative effects of drugs for children with POTS. However, a further clinical investigation is still required to better understand the pathophysiology and treatment options.

Treatment Strategies for Patients With Postural Orthostatic

Natural Remedies for POTS: Effective Solutions

儿童体位性心动过速综合征诊治策略

Frontiers A new perspective of hypothalamic disease: Shapiro's

Frontiers Autonomic Dysfunction in α-Synucleinopathies

Post-COVID Postural Orthostatic Tachycardia Syndrome and

PDF] Postural Orthostatic Tachycardia Syndrome (POTS) – A novel

A Review of Current Evaluation and Management Strategies in

Tilt table test data of ME/CFS participants and healthy controls